Lars Von Trier is a sadistic prankster auteur. Think of The Five Obstructions and extrapolate from there. He's probably going to have several laughs about reactions to his upcoming film Antichrist. No matter what the reactions turn out to be, there's probably cause for wicked glee.
Horror freaks will likely hate Von Trier's aesthetic. I suspect Antichrist's trailer might be of the Bug variety, i.e. a horror film of the soul masquerading as traditional horror (the audiences overlap slightly, but not by a lot). Jesus freaks lured by the lurid title will undoubtedly hate whatever angle Von Trier has on religiosity... at least if Breaking the Waves is any indication. Art house patrons who didn't show up for Haneke's Funny Games probably won't venture here either. Movie blogs like this one will end up in all sorts of misleading Google searches. If you've wandered here this afternoon looking for discussions of Christ's second coming and you can't wait for the world to burn so you can experience the Rapture... run away (wrong audience!). Run right to that Knowing movie instead.
Do you like the trailer? I personally can't wait to see what Von Trier does with this concept, with the "He" and "She" (no character names apparently) couple and "Eden" as setting. But you're already feeling for Charlotte Gainsbourgh I bet. If you had to live in a cabin in the woods with Willem Dafoe, wouldn't you lose your marbles?
related post: Places Willem Dafoe's Ass Has Been